Description: Don't be scammed into buying supplements that do not work. Shop with Focal Nutrition for quality, trust & peace of mind. Focal Nutrition: 100% Pure N-Acetyl L-Cysteine (NAC) 300G *Pharmaceutical Grade* PREMIUM QUALITY GUARANTEED PHARMACEUTICAL GRADE GMP-CERTIFIED MANUFACTURING 300G/ 300 SERVES FREE NEXT DAY SHIPPING N-acety L-cysteine (NAC) is an acetylated form of the amino acid L-cysteine. It's been well studies for several decades as a strong antioxidant, anti-inflammatory, and mucolytic agent (Schwalfenberg, 2021 & Birnbaum, 1957). NAC is converted to L-cysteine after ingestion, which, in turn, is converted into glutathione, a powerful antioxidant. Free L-cysteine is readily oxidized in solution, encouraging the formation of insoluble precipitates (Sheffner, 1963). In contrast, NAC is more stable and has a much lower toxicity than free L-cysteine (Gazit et al. 2003), making it safer and more effective for increasing cysteine and glutathione levels in the body. Whats included? 1 x 300g pure NAC 1 x 3g serving scoop 1 x resealable bag an silica gel for freshness 1 x free shipping Frequently asked questions What does N-acetyl L-cysteine do? NAC has cell-protective effects which work through antioxidant and anti-inflammatory mechanisms. On the antioxidant side, NAC is a potent upregulator of glutathione levels, one of the main anti-oxidants in the human body (Zhitkovich, 2019 & Oka et al. 2000). Critically, NAC is far superior at increasing glutathione levels as supplementation of glutathione direction results in compound breakdown before it can be used. Glutathione is found in every cell of the body and is intertwind with every critical process in the body from DNA synthesis to redox balance and healthy cell death (Sies, 1999). Is N-acetyl L-cysteine safe? Yes, NAC has been extensively studied for over 60 years. No adverse side effects were observed even with excessive doses 20 times higher than the 1g recommendation (Miller & Rumack, 1983). Another clincal trial reported no significant side effects at 8g/ day (Atkuri et al. 2007). However mild gastric distress may result in some individuals at these extremely high doses (Miller & Rumack, 1983 & Atkuri et al. 2007). We strongly recommend sticting to recommended dosage. How do I use it? We recommend consuming 1 gram of NAC daily at any time of day (Tenorio et al. 2021). Yes, this product is great for women as well! Should I use NAC or glutathione? It may make more sense to supplement with glutathione directly to increase glutathione levels. However, the research now shows us that supplementation of glutathione itself is rapidly broken down by the digestive tract before it can be used. NAC is far more effective at crossing across the digestive tract and increases glutathione levels far above glutathione supplementation itself! Whats your shipping arrangement? We use Australia Post for the vast majority of our deliveries. Although they aren't perfect, in our experience they provide the most consistent service, speed and affordability. From time-to-time we experience delays (especially over holiday periods), please let us know and we will do out best to help assist in getting your products delivered. Please understand that we will do our best to refund or replace lost packages, but we cannot refund in-transit purchases due to slow postage. Sincere apologies for any inconvenience caused. Disclaimer:This product does not claim to treat, diagnose, cure, or prevent any disease. The above simply details what current research has suggested. Instead, we encourage you to further explore all the scientific research, speak with a qualified healthcare professional and make an informed decision about your wellness journey. References Atkuri, K. R., Mantovani, J. J., Herzenberg, L. A., & Herzenberg, L. A. (2007). N-Acetylcysteine--a safe antidote for cysteine/glutathione deficiency. Curr Opin Pharmacol, 7(4), 355-359. Birnbaum, S. M., Winitz, M., & Greenstein, J. P. (1957). Quantitative nutritional studies with water-soluble, chemically defined diets. III. Individual amino acids as sources of non-essential nitrogen. Arch Biochem Biophys, 72(2), 428-436. Gazit, V., Ben-Abraham, R., Pick, C. G., Ben-Shlomo, I., & Katz, Y. (2003). Long-term neurobehavioral and histological damage in brain of mice induced by L-cysteine. Pharmacol Biochem Behav, 75(4), 795-799. Miller, L. F., & Rumack, B. H. (1983). Clinical safety of high oral doses of acetylcysteine. Semin Oncol, 10(1 Suppl 1), 76-85.Schwalfenberg, G. K. (2021). N-Acetylcysteine: A Review of Clinical Usefulness (an Old Drug with New Tricks). J Nutr Metab, 2021, 9949453. Oka, S.-i., Kamata, H., Kamata, K., Yagisawa, H., & Hirata, H. (2000). N-Acetylcysteine suppresses TNF-induced NF-κB activation through inhibition of IκB kinases. FEBS Letters, 472(2), 196-202. Sheffner, A. L. (1963). The Reduction In Vitro In Viscosity of Mucoprotein Solutions by a New Mucolytic Agent, N-acetyl-L-Cysteine. Ann N Y Acad Sci, 106(2), 298-310. Sies, H. (1999). Glutathione and its role in cellular functions. Free Radic Biol Med, 27(9-10), 916-921. Tenório, M., Graciliano, N. G., Moura, F. A., Oliveira, A. C. M., & Goulart, M. O. F. (2021). N-Acetylcysteine (NAC): Impacts on Human Health. Antioxidants (Basel), 10(6). Zhitkovich, A. (2019). N-Acetylcysteine: Antioxidant, Aldehyde Scavenger, and More. Chemical research in toxicology, 32(7), 1318-1319. The Focal Nutrition Difference Established in 2016, we've been providing wholesale prices and quality products across Australia. We are incredibly passionate about fitness, health and education, with the ultimate goal to improve everyone's life. Join us on our journey, as we hope to join you on yours!
Price: 39.98 AUD
Location: Melbourne, VIC
End Time: 2024-09-01T03:11:33.000Z
Shipping Cost: 29.29 AUD
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Item Specifics
Restocking fee: No
Return shipping will be paid by: Buyer
Returns Accepted: Returns Accepted
Item must be returned within: 30 Days
Main Purpose: Bodybuilding, CrossFit, Cycling, Energy Support, General Wellness, Gym & Training, Men's Health, Muscle Gain, Muscle Health, Sexual Health, Sports and Fitness Performance, Testosterone Boost, Weightlifting, Weight Management
Active Ingredients: N-Acetyl L-Cysteine
Brand: Focal Nutrition
Type: Supplement
Formulation: Powder
Ingredients: N-Acetyl L-Cysteine
Supply: 1 Month and Longer
Nutrition Facts Label: Yes
